BDBM50427337 CHEMBL2325991

SMILES COc1ccc(cc1OC)C(C)NC(=O)C1(N)CCN(CC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=IYQIOQXDNPZMSK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427337   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50427337(CHEMBL2325991)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of recombinant ROCK2 (unknown origin) using 5-FAM-labeled peptide as substrate after 1 hr by caliper off-chip incubation mobility shift as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed